Here is some very basic information I have put together about hormones.  Some of it is based on personal experience but the primary source of information....especially about dosing....is a friend who is a working pharmacist.    I hope this information is useful to you.

THE BAD STUFF

  Hormones can cause cancer in sensitive tissues.  For example taking estrogens or progesterones can cause breast cancer.  Your risk would be similar to a female sibling though, so don't worry too much, just be aware.  Estrogens can damage the kidneys and liver so its a good idea to have your blood tested every 3 months or so to monitor kidney and liver function.  Estrogens can also affect your cardiovascular (heart, blood) health.  They can increase your risk of heart attack if dosed too high too fast so beware.  One bad thing about estrogens that can happen is called Deep Vein Thrombosis.  This is a blood clot that forms in the large veins usually of the legs.  The problem with this is that the clot or a piece of it can break off and travel to the lungs where it gets trapped and cuts off blood supply to part of the lung.   This is extremely dangerous and life threatening and equires IMMEDIATE medical attention.  It starts as a sharp pain in the affected area.
  Progestins (progesterones) can cause weight gain.  Otherwise, they are pretty safe.  The only benefit in taking progestins for a TS that I have seen detailed is possible darkening and increase of size of the areola (ring around the nipple).

THE MEDIUM STUFF

  Progestins are used in combination with estrogens in post-menopausal women who still have an intact uterus.  This is because estrogens alone can cause endometrial carcinoma (cancer in the uterus tissue).  This is not a problem in M-T-F TS or TV's because there is no uterus to worry about.  Progestins also have a weak androgenic (male hormone) effect on the body.
Taking female hormones will not change the voice or facial hair.  There may also be a thinning of the scalp hair. 'Mones may cause a gradual lessening of the body hair (arms, for example).

THE GOOD STUFF

  Estrogens and progestins will cause gradual breast development which is reversible once the 'mones are stopped (up to a point). I am not sure of the reversible point, but I believe it is up to 6-to-8 months.  Breast development will be approximately 1 (ONE) cup size smaller than sisters or mother and will maximize in about 1-2 years (usually 2).
  Hormones will also cause a gradual shifting of body fat into feminine distribution patterns (away from belly towards hips).  My waist shunk and my hips grew and in my case, the results are very obvious.  Don't forget to work out!
  While on estrogens, your sexual drive will probably decline and you may notice a warm "desire" type feeling rather than "lust".  Your moods will mellow but be prepared for mood swings. Depression is a real risk in our situation partly from the change in hormonal levels, partly in response to social conditioning about what we are doing for (not to) ourselves. Having a good social or support group will help immensely with the depression.
  Spontaneous erections will cease while on estrogens and the penis will appear to shrink unless erections are achieved periodically (usually physical and psychological stimulation is required).  The testes will also begin to shrink over time. Since estrogens offset testosterone, you will also become sterile after several months of therapy. You should still orgasm, but the ejaculate will be minimal or non-existent.
  Hormones can also affect other body systems as well, including the Thyroid.   This is why it is very important to have periodic check-ups with a doctor.
  The hormones can be purchased in Mexico without a prescription and the price will vary on where you shop.  In the States, they require a prescription.  If you are doing your own dosing stick to the oral products (Premarin, Provera, or cycrin) instead of the injections.  This is because you cannot be sure what you are buying and injecting into your body unless you get it from a pharmacy.  I recommend against trying to buy injection hormones from Mexico (no guarantee of quality) but the oral tablets are fine.   Just remember that there's a danger to your kidneys and liver when self dosing.

DOSING

  The most common dose of Premarin in M-t-F is 5 mg daily. Progestins (provera or cycrin) range from 2. 5 -to- 10 mg daily and can be taken daily or cycled similar to biological levels in GG's. Cycling can give you PMS though so beware!
  Some others I have read about also use Spironolactone (Aldactone brand) or generic which helps flush the testosterone from the body. The down-side of Aldactone is electrolyte imbalances which can have serious heart problems.  I recommend you not use spironolactone unless monitored by a physician.


 
Gotta Have Boobs



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